glaucoma – Computational Ophthalmology

Policy-Driven, Multimodal Deep Learning for Predicting Visual Fields from the Optic Disc and OCT Imaging

Marian Blazes — Thu, 25 Aug 2022 23:10:37 +0000

In a new paper published in the journal Ophthalmology, Lee Lab members Yuka Kihara and Aaron Lee report the development of a novel deep learning approach to address a key problem in glaucoma research and treatment - predicting visual function from structural changes detected on optical coherence tomography (OCT). Physicians rely on visual field testing …

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Predictors of Narrow Angle Detection Rate-A Longitudinal Study of Massachusetts Residents Over 1.7 Million Person Years

Marian Blazes — Wed, 03 Jun 2020 00:08:00 +0000

In this large retrospective study published in the journal Eye, Dr. Cecilia Lee and her co-authors reviewed data from a Massachusetts claims database to assess how certain risk factors for glaucoma are detected and diagnosed during an eye exam. The authors compared outcomes from both ophthalmologists and optometrists to determine if there were any differences in how often they referred at-risk patients for further evaluation and treatment. Primary angle closure glaucoma is one of the leading causes of blindness worldwide, affecting ~26% of the glaucoma population globally. Timely detection of occludable narrow angles (condition that can sometimes progress to primary angle closure glaucoma) in patients who

Using Deep Learning to Automate Goldmann Applanation Tonometry Readings

Marian Blazes — Sat, 25 Apr 2020 23:08:00 +0000

This study describes a novel method for automating Goldman Applanation Tonometry (GAT) measurements using a deep learning approach. GAT is the gold standard method for measuring intraocular pressure, which is an essential metric in the management of glaucoma. To obtain accurate intraocular pressure measurements using traditional GAT, the user must use a dial to adjust the device to align two visible circular "mires", in order to determine the correct amount of force needed to create a fixed area of applanation

Smoking Is Associated with Higher Intraocular Pressure Regardless of Glaucoma.

Marian Blazes — Tue, 31 Mar 2020 00:40:00 +0000

Cigarette smoking is known to play a role in several ophthalmologic diseases, but reports about the effect of smoking on intraocular pressure and glaucoma have had conflicting results. In this study published in the journal Ophthalmology Glaucoma, Drs. Cecilia and Aaron Lee and their co-authors takes advantage of the American Academy of Ophthalmology IRIS (Intelligent Research in Sight) Registry, a database of 60+ million unique patients and 15,000 eye care providers to examine the connection between smoking history and intraocular pressure in more than 12 million smokers, past smokers, and nonsmokers.

Forecasting future Humphrey Visual Fields using deep learning

Marian Blazes — Sun, 14 Apr 2019 23:35:23 +0000

Glaucoma is a leading cause of blindness worldwide, and the ability to quickly anticipate future disease progression may prevent unnecessary vision loss. Humphrey visual field testing is the standard method used to evaluate disease progression in glaucoma patients. This test uses linear regression of certain global eye measurements to monitor damage and predict risk for …

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Ophthalmology-Based Neuropathology Risk Factors: Diabetic Retinopathy is Associated with Deep Microinfarcts in a Community-Based Autopsy Study.

Marian Blazes — Fri, 05 Apr 2019 23:43:00 +0000

The eye offers opportunities to capture critical information regarding the health of the brain, as the neurological anatomy and the microvasculature of the retina are very closely related to those of the brain and can be similarly affected by certain pathological processes. In this study published in the Journal of Alzheimer's Disease, Dr. Cecilia Lee …

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Associations between recent and established ophthalmic conditions and risk of Alzheimer's disease

Marian Blazes — Tue, 15 Jan 2019 20:17:00 +0000

Alzheimer's disease affects millions of adults and is the most common type of dementia. Identifying risk factors for Alzheimer's may lead to early detection and preventive measures that are based on a better understanding of the disease processes involved. The eye provides substantial information on brain health, and may give some clues to the pathogenesis …

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