In this large study using data from more than 30,000 patients in the UK, the authors analyzed potential risk factors for developing proliferative diabetic retinopathy and vitreous hemorrhage in patients with diabetes mellitus. Diabetic retinopathy is a major cause of blindness in working-age adults, and early detection can substantially decrease the risk of progression to vision loss. Patients with diabetes should have regular screening for early signs of diabetic retinopathy, but the current severity classification systems may not be the most accurate method for predicting which patients are most at risk for vision-threatening disease, particularly as standards of care have been updated.
Continue reading "The United Kingdom Diabetic Retinopathy Electronic Medical Record Users Group: Report 3: Baseline Retinopathy and Clinical Features Predict Progression of Diabetic Retinopathy"UK AMD/DR EMR REPORT IX: comparative effectiveness of predominantly as needed (PRN) ranibizumab versus continuous aflibercept in UK clinical practice
In this multicenter study in the UK, the authors analyzed the electronic medical records of patients with age-related macular degeneration and compared two different drugs, ranibizumab and aflibercept, commonly used to treat this disease. Neovascular age-related macular degeneration is characterized by choroidal neovascularisation, which is responsible for the majority of visual loss. Intravitreal injections with vascular endothelial growth factor-A inhibitor drugs can reduce abnormal blood vessel growth and improve vision. This studied compared the effectiveness of two of these drugs, ranibizumab and aflibercept, by analyzing the visual acuity outcomes in patients who received either drug over a one year period.
Continue reading "UK AMD/DR EMR REPORT IX: comparative effectiveness of predominantly as needed (PRN) ranibizumab versus continuous aflibercept in UK clinical practice"Validation of the Total Visual Acuity Extraction Algorithm (TOVA) for Automated Extraction of Visual Acuity Data From Free Text, Unstructured Clinical Records
In this study, the authors created and tested an algorithm for extracting visual acuity testing information from clinical notes. The increasing use of electronic health records is allowing for large-scale data review in clinical research. The data accessed from electronic health records can be limited, however, because the manually transcribed data is often stored as free text. Automated conversion of free text into machine-readable data and extraction for research requires the application of computational linguistics and natural language processing.
Continue reading "Validation of the Total Visual Acuity Extraction Algorithm (TOVA) for Automated Extraction of Visual Acuity Data From Free Text, Unstructured Clinical Records"Deep learning is effective for the classification of OCT images of normal versus Age-related Macular Degeneration
Optical coherence tomography (OCT) is the most commonly obtained imaging modality in ophthalmology and represents a dense and rich imaging dataset when combined with labels derived from the electronic medical record. In this study, the authors developed a novel deep learning approach to distinguish normal OCT images from images from patients with age-related macular degeneration.
Continue reading "Deep learning is effective for the classification of OCT images of normal versus Age-related Macular Degeneration"Evaluating Access to Eye Care in the Contiguous United States by Calculated Driving Time in the United States Medicare Population
In this important study, Dr. Cecilia Lee, Dr. Aaron Lee, and their co-authors used census and mapping data to quantify how far Medicare patients travel to access eye care in the contiguous United States. This type of information about medically underserved geographic areas is essential for improving access to care. The authors note that the issue of rural access to care has been cited as a reason for increasing the number of eye care providers in the United States. Some providers also use access to care as an argument for increasing optometrists' responsibilities and scope of practice.
Continue reading "Evaluating Access to Eye Care in the Contiguous United States by Calculated Driving Time in the United States Medicare Population"